Ooooooo, I like this thread. Really tough to pick favorites, especially with the girls, I legitimately love them all and will support anyone in their best girl pick.
Best Girl: Sakura Ogami
Best Boy: Byakuya Togami
Best Trial: Chapter 3, because it was so satisfying to out the culprit, watching them crack was the best, and I appreciated the multi-tiered killings.
Best Girl: Chiaki Nanami
Best Boy: Gundham Tanaka
Best Trial: Chapter 2, because of Twilight Syndrome Murder Case. It really put the wheels in motion for the whole backstory with these characters being revealed.
Least Favorite moments... Mecha Nekomaru. I normally love my robots, and they are usually an easy sell, but this just never really clicked. It certainly has a place thematically but it just didn't work for me unfortunately.