What games would you want to play? Here's my personal list to kick things off:
Shin Megami Tensei: Digital Devil Saga 1 and 2 - I feel like I'm obligated to play some Shin Megami Tensei game on stream, and I think these make a good introductory set. They're not as long as Nocturne or Persona, they're a little under the radar, and I think I could keep things moving at a nice pace without too much grinding.
Metroid Prime 1, 2, and 3 - Partially because I just don't see anyone playing these games. Metroid Prime was my favorite game of all time for ages, and it might still be at the top of my list. I know the game front to back, and can pretty effortlessly hit mid 90's in completion percentage, so again, I think I could keep the flow from getting too stale.
Metroid Fusion - nice little bite-sized 2 hour game after the number of times I've gone through it.
Mega Man Zero 3 - this one's a little complicated. I'm not too bad at this game, but it requires a lot of memorization to be effective at, and my standards for end-of-chapter scores are very high when it comes to my own personal playthroughs. I think if I were to do this one, I'd have to start a poll to ask what sorts of rules the chat would like me to play under - no subtanks, restart the stage after death, A rank only, S rank only, and so on.
Legend of Dragoon - This was my first RPG, so I hold it near and dear to my heart. Grinding additions could cause it to drag, but I think the game itself doesn't require too much effort, so it'd probably be pretty fun.
Outland - a Metroid-meets-Ikaruga style game by Housemarque that I liked quite a lot. Another game that I feel like nobody talks about, so I'd like to give it some exposure.
Sonic 3 and Knuckles - this game embodies my childhood, so it'd be fun to run through it every now and again. I play it a couple times a year, anyway.
Tales of Xillia - probably just so I could get my thoughts on the game out. After Symphonia, I had never managed to finish another Tales game until I bought Xillia on a whim. It gripped me pretty thoroughly.
That's a start, anyway. So, yeah, let's start a discussion!