Final Fantasy X
A love of jrpgs. It was a close tie between X and Mario RPG. But I'd say X has a slightly closer place in my heart. I'm even going through it right now for my probably 5th or 6th time.
Legend of Zelda: Majora's Mask
Good ol' Nintendo action adventure.
With an occasionally creepy psychedelic twist. Talk about meaningful sidequests!
Assassins Creed 2
Encompassing the open world genre. I could climb towers for days. (Maybe only a few at a sitting though :p)
Metroid Prime 2
Besides Goldeneye, one of the first fps I can remember playing. Definitely left a favorable impact. Also had some great puzzles.. I'm including Metroidvanias in here too. It's not a 2D one, but it does have the name in the title lol.
Life is Strange
For the modern story driven adventure games.